Forskolin
Application Notes
Forkolin is reported to demonstrate positive inotropic and heart rate-increasing activity at low doses in animals. Also functions as an antihypertensive and vasodilator at higher doses. Activates adenylcyclase in rat liver membranes.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antihypertensive | Vasodilator
| SKU | 02190669-CF |
| Alternate Names | 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one; Coleonol; Colforsin |
| Application Notes | Forkolin is reported to demonstrate positive inotropic and heart rate-increasing activity at low doses in animals. Also functions as an antihypertensive and vasodilator at higher doses. Activates adenylcyclase in rat liver membranes. |
| Base Catalog Number | 190669 |
| Beilstein Registry Number | 1692716 |
| Biochemical Physiological Actions | Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase. |
| CAS # | 66575-29-9 |
| EC Number | 266-410-9 |
| Hazard Statements | H312 |
| Molecular Formula | C22H34O7 |
| Molecular Weight | 410.507 g/mol |
| Personal Protective Equipment | Dust mask type , Eyeshields, Gloves |
| RTECS Number | QL6150000 |
| Safety Symbol | GHS07 |
| Source | Coleus forskohlii |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |