Leupeptin hemisulfate
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SKU: 02151553-CF
Product Description
Leupeptin Hemisulfate
Application Notes
Leupeptin is a Inhibitor for trypsin, plasmin, papain, and cathepsin B.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Inhibitor
Specifications
| SKU | 02151553-CF |
| Alternate Names | Acetyl-Leu-Leu-Arg-al |
| Application Notes | Leupeptin is a Inhibitor for trypsin, plasmin, papain, and cathepsin B. |
| Base Catalog Number | 151553 |
| Biochemical Physiological Actions | Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.) |
| CAS # | 103476-89-7 |
| Molecular Formula | C20H38N6O4 • 1/2H2SO4 |
| Molecular Weight | 951.196 g/mol |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| Typical Working Concentration | Effective concentration 10-100 μM. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
Datasheet
Datasheet
Safety Data Sheets
English (United States)