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    4-Aminopyridine

    As low as A$76.64
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    SKU:  02150366-CF

    Synonyms
    Amino-4-Pyridine; γ-Aminopyridine; 4-Pyridinamine, 4-Pyridylamine; Fampridine; 4AP
    CAS Number:
    504-24-5
    Molecular Formula:
    C5H6N2
    Molecular Weight:
    94.13
    Beilstein Registry Number:
    105782
    EC Number:
    207-987-9
    MDL Number:
    MFCD00006439
    Packaging size:
    100 g
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    Specifications
    SKU 02150366-CF
    Alternate Names Amino-4-Pyridine; γ-Aminopyridine; 4-Pyridinamine, 4-Pyridylamine; Fampridine; 4AP
    Application Notes 4-Aminopyridine (4-AP) is a nonselective K+ channel blocker that has been used to characterize and study the blockage of K+ channels. Studies show that 4-AP binds from the cytoplasmic side of the cell membrane. Research suggest that 4-AP extends the potentials of unmyelinated and demyelinated fibers, facilitates conduction in fibers blocked by demyelination, and can induce glutamate and neurotransmitter γ-aminobutyric acid (GABA) release.
    Base Catalog Number 15036680
    Beilstein Registry Number 105782
    Biochemical Physiological Actions 4-aminopyridine (4-AP) is a non-selective potassium channel blocker. It reverses saxitoxin and tetrodotoxin induced cardiorespiratory depression. 4-AP increases stimulation-induced release of acetylcholine and induces depolarization of GABA neurons.
    Boiling Point 273 °C (Lit.)
    CAS # 504-24-5
    EC Number 207-987-9
    Extinction Coefficient EmM = 16.6 (0.1 M HCl), 17.4 (0.1 M HCl)(Lit.)
    Hazard Statements H300-H315-H319-H335
    Melting Point 153 -163 °C
    Molecular Formula C5H6N2
    Molecular Weight 94.13
    Pack Size 100 g
    Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves, respirator cartridges
    pH 10.5 - 11.5 (1% aq. soln.)
    Purity ~98%
    RTECS Number US1750000
    Safety Symbol GHS06
    Solubility Soluble in water (50 mg/mL - clear and colorless), 100% ethanol, methanol (slightly), alcohol, and DMSO (100 mM), slightly soluble in benzene, ether; very slighly soluble in ligroin.
    Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
    UV Visible Absorbance λ max: 263 nm (0.1 M HCl), 262 nm (0.1 M HCl)(Lit.)
    Documents

    Certificate of Analysis (COA)

    MP COA [150366] lot ID: R27900 MP COA [150366] lot ID: R27900
    02150366-U1124157932 CoA.pdf 02150366-U1124157932 CoA.pdf
    SR05746.pdf SR05746.pdf

    Datasheet

    Datasheet
    DS [02150366] DS [02150366]