Leupeptin hydrochloride, ≥60%
SKU: 02195624-CF
Leupeptin Hydrochloride
Application Notes
Leupeptin Hydrochloride is used in immunoblotting and acts as a Protease inhibitor.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Immunoblotting | Protease Inhibitor
| SKU | 02195624-CF |
| Alternate Names | Acetyl-Leu-Leu-Arg-al hydrochloride |
| Application Notes | Leupeptin Hydrochloride is used in immunoblotting and acts as a Protease inhibitor. |
| Base Catalog Number | 195624 |
| Biochemical Physiological Actions | Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.) |
| CAS # | 24125-16-4 |
| Molecular Formula | C20H38N6O4·HCl |
| Molecular Weight | 463.02 g/mol |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| Purity | ≥60% |
| Typical Working Concentration | Effective concentration is typically 10-100 uM. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |