5-Fluorodeoxyuridine

Name: 5-Fluorodeoxyuridine
SKU: 02105551-CF
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SKU: 02105551-CF

Key features and details

5-Fluorodeoxyuridine

Synonyms

2'-Deoxy-5-Fluorouridine; Floxuridine; 5-Fluoro-2'-deoxyuridine; FUDR; dFUR

CAS Number:

50-91-9

Molecular Formula:

C9H11FN2O5

Molecular Weight:

246.194 g/mol

Beilstein Registry Number:

90221

EC Number:

200-072-5

MDL Number:

MFCD00006530

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Product Description

5-Fluorodeoxyuridine

Application Notes

5-Fluorodeoxyuridine can be used to target thymidylate synthetase in cancer chemotherapy. Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chemotherapy

Specifications

SKU	02105551-CF
Alternate Names	2'-Deoxy-5-Fluorouridine; Floxuridine; 5-Fluoro-2'-deoxyuridine; FUDR; dFUR
Application Notes	5-Fluorodeoxyuridine can be used to target thymidylate synthetase in cancer chemotherapy. Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.
Base Catalog Number	105551
Beilstein Registry Number	90221
Biochemical Physiological Actions	Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase. Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.
CAS #	50-91-9
EC Number	200-072-5
Extinction Coefficient	EmM = 8.91 (0.1 M phosphate buffer, pH 6.0) (Lit.)
Format	Powder
Hazard Statements	H301
Melting Point	302 to 304° F (NTP, 1992)
Molecular Formula	C9H11FN2O5
Molecular Weight	246.194 g/mol
Optical Rotation	+37 ° (10 mg/mL in water at 25 °C) (Lit.)
Personal Protective Equipment	Dust mask , Eyeshields, Faceshields, Gloves
pKa	7.6 (Lit.)
Purity	>98%
RTECS Number	YU7525000
Safety Symbol	GHS06
Solubility	Water Solubility11900 mg/L
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance	λmax (water) : 266 - 270 nm
Vapor Pressure	7.6X10-13 mm Hg at 25 deg C (est)