Neomycin sulfate, USP
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SKU: 02180610-CF
Specifications
| SKU | 02180610-CF |
| Application Notes | Neomycin Trisulfate is produced by Streptomyces containing a minimum of 85% neomycin B. It has been used as a selection agent for prokaryotic cells transformed using the neo selectable marker gene, and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins. |
| Base Catalog Number | 180610 |
| Biochemical Physiological Actions | Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons. |
| CAS # | 1405-10-3 |
| EC Number | 215-773-1 |
| Format | Powder |
| Grade | USP |
| Hazard Statements | H317-H334 |
| Molecular Formula | C23H46N6O13 • 3H2SO4 |
| Molecular Weight | 908.9 |
| Personal Protective Equipment | dust mask, Eyeshields, Faceshields, Gloves |
| pH | 5-7.5 |
| Safety Symbol | GHS08 |
| Solubility | H2O: soluble50 mg/mL |
| Specific Activity | ≥600 µg/mg |
| Typical Working Concentration | It is recommended for use in cell culture applications at 50 mg/L. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
Safety Data Sheets
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