Congo Red
SKU: 02105099-CF
Congo Red
Application Notes
In biochemistry and histology, congo red is used to stain microscopic preparates, especially as a cytoplasm and erythrocyte stain. It is used for the visual detection of amyloid in muscle and nerve fresh frozen sections in patients who have amyloidosis. Apple-green birefringence of Congo red stained preparates under polarized light is indicative for the presence of amyloid fibrils. Additionally, congo red is used in microbiological epidemiology to rapidly identify the presence of virulent serotype 2a Shigella flexneri, where the dye binds the bacterium's unique lipopolysaccharide (LPS) structure.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Detection of amyloid | Indicator in testing for free hydrochloric acid in gastric contents
| SKU | 02105099-CF |
| Alternate Names | Cotton Red; Benzo Congo Red; Direct Red 28; C.I. 22120; Sodium Diphenyldiazo-bis(alpha-NAPH-Thylaminesulfonate); Congo Red 4B; Cosmos Red; Direct Red R; Direct Red Y; Cotton Red B; Cotton Red C |
| Application Notes | In biochemistry and histology, congo red is used to stain microscopic preparates, especially as a cytoplasm and erythrocyte stain. It is used for the visual detection of amyloid in muscle and nerve fresh frozen sections in patients who have amyloidosis. Apple-green birefringence of Congo red stained preparates under polarized light is indicative for the presence of amyloid fibrils. Additionally, congo red is used in microbiological epidemiology to rapidly identify the presence of virulent serotype 2a Shigella flexneri, where the dye binds the bacterium's unique lipopolysaccharide (LPS) structure. |
| Base Catalog Number | 105099 |
| Beilstein Registry Number | 3894858 |
| CAS # | 573-58-0 |
| Color Index | 22120 |
| EC Number | 209-358-4 |
| Format | Powder |
| Hazard Statements | H350-H361d |
| Melting Point | >360 deg C |
| Molecular Formula | C32H22N6Na2O6S2 |
| Molecular Weight | 696.664 g/mol |
| Personal Protective Equipment | Eyeshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter |
| pH | SOLN HAVE PH OF 8-9.5 |
| RTECS Number | QK1400000 |
| Safety Symbol | GHS08 |
| Solubility | Sol in <a class="pubchem-internal-link CID-702" href="https://pubchem.ncbi.nlm.nih.gov/compound/ethanol">ethanol</a>; very slightly sol in <a class="pubchem-internal-link CID-180" href="https://pubchem.ncbi.nlm.nih.gov/compound/acetone">acetone</a>; practically insol in ether |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | λ max (water): 497 ± 3nm |
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