Thapsigargin

Application Notes

Thapsigargin may be used to distinguish between discrete intracellular Ca2+ pools. It induces apoptosis in rat thymocytes and in human hepatoma cells.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Apoptosis inducer | Calcium releaser

SKU	02158999-CF
Application Notes	Thapsigargin may be used to distinguish between discrete intracellular Ca2+ pools. It induces apoptosis in rat thymocytes and in human hepatoma cells.
Base Catalog Number	158999
Biochemical Physiological Actions	Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. Induces apoptosis by disrupting intracellular free Ca2+ levels; incorporated into chemotherapeutic prodrug formulations.
CAS #	67526-95-8
Format	Crystalline powder
Hazard Statements	H315-H319-H334-H335
Molecular Weight	650.762 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Faceshields, Gloves
Purity	≥97%
Refractive Index	n20D 1.54 (Predicted)(Lit.)
Safety Symbol	GHS07, GHS08
Source	Thapsia garganica
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.