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Menadione is a prothrombogenic compound1 and is used as a model quinone in cell culture and in vivo investigations.
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|Alternate Names||Vitamin K3; 2-Methyl-1,4-naphthoquinone|
|Application Notes||Menadione is a prothrombogenic compound1 and is used as a model quinone in cell culture and in vivo investigations.|
|Base Catalog Number||102259|
|Beilstein Registry Number||1908453|
|Biochemical Physiological Actions||Menadione (Vitamin K3) is a synthetic analogue of of 1,4-naphthoquinone with a methyl group in the 2-position. Menadione is used as a phosphatase inhibitor and an inhibitor of mitochondrial DNA polymerase γ (pol γ). Menadione can be used as an oxidative injury (free radical generator) inducing agent.|
|Melting Point||107 Â°C|
|Molecular Weight||172.183 g/mol|
|Personal Protective Equipment||Dust mask , Eyeshields, Faceshields, Gloves|
|pH||Alc soln is neutral to litmus|
|Solubility||<h5 class="minor-section-title">Water Solubility</h5>160 mg/L (at 30 Â°C)|