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Bumetanide

Bumetanide

$70.90
Bumetanide

SKU: 02154263-CF

Synonyms
Ro 10-6338; 3-(aminosulfonyl)-5-(butylamino)- 4-phenoxybenzoic acid; 3-(butylamino)-4-phenoxy- 5-sulfamoylbenzoic acid
CAS Number:
28395-03-1
Molecular Formula:
C17H20N2O5S
Molecular Weight:
364.416 g/mol
EC Number:
249-004-6
MDL Number:
MFCD00078949
Product Description

Bumetanide

Application Notes

Bumetanide has been used to probe the role of prostaglandin E2 in the regulation of chloride secretion across porcine endometrial epithelial cells. A study of the effects of bumetanide application and subsequent sodium potassium chloride cotransporter (NKCC1) inhibition in cultured liver cells has indicated increased α1-smooth muscle actin expression in 2-day-cultured hepatic stellate cells. An investigation of lactacidosis treatment of suspended G6 glial cells with bumetanide included at 0.1 mM has shown diminished cell swelling due to lactacidosis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02154263-CF
Alternate Names Ro 10-6338; 3-(aminosulfonyl)-5-(butylamino)- 4-phenoxybenzoic acid; 3-(butylamino)-4-phenoxy- 5-sulfamoylbenzoic acid
Application Notes Bumetanide has been used to probe the role of prostaglandin E2 in the regulation of chloride secretion across porcine endometrial epithelial cells. A study of the effects of bumetanide application and subsequent sodium potassium chloride cotransporter (NKCC1) inhibition in cultured liver cells has indicated increased α1-smooth muscle actin expression in 2-day-cultured hepatic stellate cells. An investigation of lactacidosis treatment of suspended G6 glial cells with bumetanide included at 0.1 mM has shown diminished cell swelling due to lactacidosis.
Base Catalog Number 154263
Biochemical Physiological Actions Inhibitor of Na+/K+/Cl- cotransporter.
CAS # 28395-03-1
EC Number 249-004-6
Format Powder
Melting Point 230-231
Molecular Formula C17H20N2O5S
Molecular Weight 364.416 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Purity ≥99%
RTECS Number DG4910000
Solubility >54.7 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

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