Erythromycin, cell culture reagent, ~98%, 5 g
SKU: 0219452905
Erythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis. This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus. It is a mixture consisting largely of erythromycin A with lesser amounts of erythromycins B and C.
Application Notes
Used in cell culture applications at approximately 100 mg/liter. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
| SKU | 0219452905 |
| Alternate Names | E- mycin; Erycin; Robimysin; Erythrocin |
| Application Notes | Used in cell culture applications at approximately 100 mg/liter. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria. |
| Base Catalog Number | 19452905 |
| Beilstein Registry Number | 75279 |
| Biochemical Physiological Actions | Mode of Action: Inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site). Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
| CAS # | 114-07-8 |
| EC Number | 204-040-1 |
| Extinction Coefficient | EM = 50 (280 nm, pH 6.3) |
| Grade | Cell Culture Grade |
| Melting Point | 135 to 140 °C (Lit.) |
| Molecular Formula | C37H67NO13 |
| Molecular Weight | 733.95 |
| Optical Rotation | -71° to -78° (c=2, ethanol) |
| Pack Size | 5 g |
| Personal Protective Equipment | Eyeshields, Gloves, Respirator filter |
| pH | 8.0 - 10.5 (70% aq soln) |
| pKa | 8.8 |
| Potency | ≥850 ug/mg |
| Purity | 98% |
| RTECS Number | KF4375000 |
| Solubility | Slightly soluble in water (~2 mg/mL); Moderately soluble in ether, ethylene dichloride, amyl acetate; freely soluble in alcohols (ethanol - 50 mg/mL), acetone, chloroform, acetonitrile, ethyl acetate. Soluble in 2 M Hydrochloric acid (50 mg/mL). |
| Typical Working Concentration | Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
![MP COA [194529] lot ID: QR13827](https://www.mpbio.com/static/version1780565991/frontend/Mpbio/luma/en_US/images/document.png "MP COA [194529] lot ID: QR13827")
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