Glucagon is a hormone that is secreted by α cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagon's hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.
Application Notes
Anti-Glucagon Polyclonal is used for immunostaining of acetone-fixed frozen and formalin-fixed, paraffin-embedded tissue sections.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Immunohistochemistry (Paraffin; Acetone Fixed) |Immunohistochemistry (Frozen)
| SKU | 0811184 |
| Alternate Names | GCG antibody; Glicentin related polypeptide antibody; GLP 1 antibody; GLP 2 antibody; Glucagon like peptide 1 antibody; Glucagon like peptide 2 antibody; Glucagon precursor antibody; GRPP antibody |
| Antibody Type | Polyclonal Antibody |
| Application Notes | Anti-Glucagon Polyclonal is used for immunostaining of acetone-fixed frozen and formalin-fixed, paraffin-embedded tissue sections. |
| Base Catalog Number | 11184 |
| Conjugate | Unconjugated |
| Format | lyophilized |
| Formulation Details | Liquid |
| Grade | Molecular Grade |
| Host | Rabbit |
| Immunogen | Porcine pancreatic Glucagon/BSA |
| Isotype | IgG |
| Pack Size | 250 µL |
| Solubility | Soluble in Water |
| Species Reactivity | Porcine |
| Specificity | Reactive in human and rat. The antiserum cross-reacts with human and rat tissues. It reacts with glucagon in the α-cells of the pancreatic islets and in the endocrine cells of the gut and in neurons in the brain. |
| Typical Working Concentration | Dilution: 1:50 (Indirect method, 60 minute incubation). Note: With a normal ABC method the dilution can be 5-10 times higher |
| Uniprot Number | SwissProt ID: (Hu) P01275, (Ms) P55095, (Rt) P06883 |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
![MP COA [11184] lot ID: 1056B](https://www.mpbio.com/static/version1742546773/frontend/Mpbio/default/en_US/images/document.png "MP COA [11184] lot ID: 1056B")
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