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Elastatinal, ≥50%, 1 mg

Elastatinal, ≥50%, 1 mg
€20.60

SKU: 0215284701

Synonyms
(2S)-2-[(4S)-2-Amino-1,4,5,6-tetrahydro4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl-L-glutamamide; N-(Nα-Carbonyl-Cpd-Gln-Ala-al)-Leu where Cpd = capreomycidine = (S,S)-α-[2-Iminohexahydro-4-pyrimidylglycine]
CAS Number:
51798-45-9
Molecular Formula:
C21H36N8O7
Molecular Weight:
512.57
Beilstein Registry Number:
873543
EC Number:
257-426-7
Packaging size:
1 mg
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Specifications
SKU 0215284701
Alternate Names (2S)-2-[(4S)-2-Amino-1,4,5,6-tetrahydro4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl-L-glutamamide; N-(Nα-Carbonyl-Cpd-Gln-Ala-al)-Leu where Cpd = capreomycidine = (S,S)-α-[2-Iminohexahydro-4-pyrimidylglycine]
Base Catalog Number 15284701
Beilstein Registry Number 873543
Biochemical Physiological Actions Potent, irreversible elastase inhibitor (Ki = 240 nM). Elastatinal is a much stronger inhibitor of elastase from pancreas than from leucocytes. Elastatinal is a strong competitive inhibitor of elastase which is found in some species of Streptomyces, showing 50% inhibition at 0.29 ug/mL, while greater than 250 ug/mL is required for other proteases.
CAS # 51798-45-9
EC Number 257-426-7
Extinction Coefficient E1% = 1.5 (0.1 N HCl), 2.5 (0.1 M phosphate, pH 7.0)(Lit.)
Molecular Formula C21H36N8O7
Molecular Weight 512.57
Pack Size 1 mg
Personal Protective Equipment Eyeshields, Gloves, respirator filter
pKa 3.7 and >10.5 (Lit.)
Purity ≥50%
RTECS Number LZ9600000
Solubility Soluble in water (20 mg/mL - clear solution), DMSO, or methanol. Also soluble in pyridine, dimethyl sulfoxide, and slightly soluble in ethanol.
Typical Working Concentration Effective concentration is typically 0.5 to 2 ug/mL.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λmax: 275 nm, 298 nm (Lit.)
Documents

Datasheet

Datasheet
DS [02152847] DS [02152847]