1,1-Dimethylbiguanide hydrochloride

Product Description

1,1-Dimethylbiguanide Hydrochloride

Application Notes

1,1-Dimethylbiguanide Hydrochloride has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

An antidiabetic agent

Specifications

SKU	02157805-CF
Alternate Names	N,N-Dimethylimidodicarbonimidic diamine; 1,1-Dimethylbiguanide hydrochloride; DMGG; LA-6023; Metformin hydrochloride
Application Notes	1,1-Dimethylbiguanide Hydrochloride has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
Base Catalog Number	157805
Biochemical Physiological Actions	1,1-Dimethylbiguanide hydrochloride (Metformin) is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
CAS #	1115-70-4
EC Number	214-230-6
Format	Powder
Hazard Statements	H302-H315-H319
Molecular Formula	C4H12ClN5
Molecular Weight	165.625 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Gloves
RTECS Number	DU1800000
Safety Symbol	GHS07
Solubility	In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 1.06X10+6 mg/L (miscible) at 25 deg C (est)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure	7.58X10-5 mm Hg at 25 deg C (est)