Vinblastine sulfate

Name: Vinblastine sulfate
SKU: 02190287-CF
Price: 36.58 USD

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SKU: 02190287-CF

Key features and details

Vinblastine Sulfate

Synonyms

VLB; Vincaleukoblastine sulfate salt

CAS Number:

143-67-9

Molecular Formula:

C46H60N4O13S

Molecular Weight:

909.061 g/mol

Beilstein Registry Number:

3659812

EC Number:

205-606-0

MDL Number:

MFCD00082457

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Product Description

Vinblastine Sulfate

Application Notes

Vinblastine Sulfate is used in cancer research.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used in cancer research

Specifications

SKU	02190287-CF
Alternate Names	VLB; Vincaleukoblastine sulfate salt
Application Notes	Vinblastine Sulfate is used in cancer research.
Base Catalog Number	190287
Beilstein Registry Number	3659812
Biochemical Physiological Actions	Plant alkaloid that inhibits microtubule assembly by binding tubulin and inducing self-association in spiral aggregates in a reaction that appears to be regulated by the C-terminus of β-tubulin and is enhanced by GDP and GTP. Depolymerizes microtubules. Arrests the cell cycle in G2/M-phase by blocking mitotic spindle formation. Triggers Raf-1 activation, phosphorylation of bcl-2-family proteins, induction of p53 expression, and apoptosis in several tumor cell lines. Substrate of Pgp and CYP3A4.
CAS #	143-67-9
EC Number	205-606-0
Format	Powder
Hazard Statements	H302-H315-H318-H335
Melting Point	543 to 545° F (NTP, 1992)
Molecular Formula	C46H60N4O13S
Molecular Weight	909.061 g/mol
RTECS Number	YY8400000
Safety Symbol	GHS05, GHS07
Solubility	greater than or equal to 10 mg/mL at 76.1° F (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.