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Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.
Antipernicious anemia factor | Cofactor | Treatment of vitamin B12 deficiency; cyanide poisoning; and hereditary deficiency of transcobalamin II
|Alternate Names||Cyanocobalamin; α-(5,6-Dimethylbenzimidazolyl)cyanocobamide; CN-Cbl; Cyanocob(III)alamin|
|Application Notes||Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.|
|Base Catalog Number||103271|
|Beilstein Registry Number||4122889|
|Biochemical Physiological Actions||Biosynthesis of the basic structure of the vitamin is accomplished only by bacteria(which usually produce hydroxocobalamin). Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.|
|Boiling Point||> 300 deg C|
|Melting Point||> 300 Â°C|
|Molecular Weight||1355.388 g/mol|
|Personal Protective Equipment||Eyeshields, Gloves, respirator filter|
|pH||Commercially available <a class="pubchem-internal-link multiple-CIDs" href="https://pubchem.ncbi.nlm.nih.gov/compound/cyanocobalamin">cyanocobalamin</a> for injection has a pH of 4.5-7|
|Solubility||<h5 class="minor-section-title">Water Solubility</h5>12500 mg/L|