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Tamoxifen

Tamoxifen

Synonyms [Z]-1-[p-Dimethylaminoethoxyphenyl]-1,2-diphenyl-1-butene; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; ICI 47699; trans-Tamoxifen; Z-Tamoxifen; (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine; trans-1-(p-b- Dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene citrate

CAS Number: 10540-29-1 Molecular Formula: C26H29NO Molecular Weight: 371.524 g/mol

EC Number: 234-118-0 MDL Number: MFCD00010454

SKU 02156738-CF
$40.75
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Description

Product Description

Tamoxifen

Application Notes

Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antifungal | Antineoplastic | Immunosuppressive Antibiotics

Specifications
SKU 02156738-CF
Alternate Names [Z]-1-[p-Dimethylaminoethoxyphenyl]-1,2-diphenyl-1-butene; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; ICI 47699; trans-Tamoxifen; Z-Tamoxifen; (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine; trans-1-(p-b- Dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene citrate
Application Notes Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Base Catalog Number 156738
Biochemical Physiological Actions Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
CAS # 10540-29-1
EC Number 234-118-0
Hazard Statements H350-H360-H362
Melting Point 97 °C
Molecular Formula C26H29NO
Molecular Weight 371.524 g/mol
Personal Protective Equipment Eyeshields, full-face particle respirator, Gloves, respirator cartridge , respirator filter, respirator cartridges
pKa approximately 8.85; approximately 6.9 (in Triton® X-100)
RTECS Number KR5919600
Safety Symbol GHS08
Solubility 2.6 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 3.46X10-8 mm Hg at 25 deg C (est)