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Rotenone is utilized as an insecticide. It can be used as neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
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Insectiside | Piscicide | Neurotoxic agent
|Alternate Names||[2R-(2.a, 6a.a,12a.a)]-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)- benzopyrano[3,4-b] furo[2,3-h]  benzopyran-6(6aH)-one; Canex (Pitman-Moore)|
|Application Notes||Rotenone is utilized as an insecticide. It can be used as neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.|
|Base Catalog Number||150154|
|Beilstein Registry Number||6773081|
|Biochemical Physiological Actions||Inhibitor of mitochondrial electron transport at NADH: ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.|
|Boiling Point||410 to 428Â° F at 0.5 mm Hg (NTP, 1992)|
|Density||1.27 at 68Â° F (NTP, 1992)|
|Extinction Coefficient||19.2 (294 nm, ethanol)(Lit.)|
|Melting Point||329 to 331Â° F (NTP, 1992)|
|Molecular Weight||394.423 g/mol|
|Optical Rotation||-120° (1.38 g/100 mL chloroform at 25 °C) (Lit.)|
|Partition Coefficient||Octanol/Water Partition Coefficient-log Kow = 4.10 (Lit.)|
|Safety Symbol||GHS06, GHS09|
|Solubility||less than 1 mg/mL at 68Â° F (NTP, 1992)|
|Vapor Pressure||less than 0.0075 mm Hg at 68Â° F (NTP, 1992)|