Retinoic Acid (all trans)

Name: Retinoic Acid (all trans)
SKU: 02190269-CF
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SKU: 02190269-CF

Key features and details

Retinoic Acid, All Trans Isomer

Synonyms

Vitamin A acid; Tretinoin; ATRA; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8 -nonatetraenoic acid; Aberel; Airol; Aknoten; Cordes Vas; Dermairol; Retin-A; Vesnaroid

CAS Number:

302-79-4

Molecular Formula:

C20H28O2

Molecular Weight:

300.442 g/mol

Beilstein Registry Number:

2057223

EC Number:

206-129-0

MDL Number:

MFCD00001551

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Product Description

Retinoic Acid, All Trans Isomer

Application Notes

Retinoic Acid has been used in various differentiation protocols, including B-cells, T cells and neurons and applied clinically to treat cancer as a form of differentiation-induction therapy.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Signaling molecule | Cancer Research

Specifications

SKU	02190269-CF
Alternate Names	Vitamin A acid; Tretinoin; ATRA; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8 -nonatetraenoic acid; Aberel; Airol; Aknoten; Cordes Vas; Dermairol; Retin-A; Vesnaroid
Applications	Signaling molecule \| Cancer Research
Application Notes	Retinoic Acid has been used in various differentiation protocols, including B-cells, T cells and neurons and applied clinically to treat cancer as a form of differentiation-induction therapy.
Base Catalog Number	190269
Beilstein Registry Number	2057223
Biochemical Physiological Actions	All−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.
CAS #	302-79-4
EC Number	206-129-0
Hazard Statements	H302
Melting Point	354 to 360° F (NTP, 1992)
Molecular Formula	C20H28O2
Molecular Weight	300.442 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Gloves
RTECS Number	VH6475000
Safety Symbol	GHS07
Solubility	less than 1 mg/mL at 77° F (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance	λ max (isopropanol + sulfuric acid)=353 ± 3 nm
Vapor Pressure	2.4X10-7 mm Hg @ 25 deg C /Estimated/