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Retinol (all trans)

Retinol (all trans)

Synonyms Vitamin A acid; Tretinoin; ATRA; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8 -nonatetraenoic acid; Aberel; Airol; Aknoten; Cordes Vas; Dermairol; Retin-A; Vesnaroid

CAS Number: 302-79-4 Molecular Formula: C20H28O2 Molecular Weight: 300.442 g/mol

Beilstein Registry Number: 2057223 EC Number: 206-129-0 MDL Number: MFCD00001551

SKU 02190269-CF
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Description

Product Description

Retinoic Acid, All Trans Isomer

Application Notes

Retinoic Acid has been used in various differentiation protocols, including B-cells, T cells and neurons and applied clinically to treat cancer as a form of differentiation-induction therapy.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Signaling molecule | Cancer Research

Specifications
SKU 02190269-CF
Alternate Names Vitamin A acid; Tretinoin; ATRA; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8 -nonatetraenoic acid; Aberel; Airol; Aknoten; Cordes Vas; Dermairol; Retin-A; Vesnaroid
Application Notes Retinoic Acid has been used in various differentiation protocols, including B-cells, T cells and neurons and applied clinically to treat cancer as a form of differentiation-induction therapy.
Base Catalog Number 190269
Beilstein Registry Number 2057223
Biochemical Physiological Actions All−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.
CAS # 302-79-4
EC Number 206-129-0
Hazard Statements H302
Melting Point 354 to 360° F (NTP, 1992)
Molecular Formula C20H28O2
Molecular Weight 300.442 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
RTECS Number VH6475000
Safety Symbol GHS07
Solubility less than 1 mg/mL at 77° F (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max (isopropanol + sulfuric acid)=353 ± 3 nm
Vapor Pressure 2.4X10-7 mm Hg @ 25 deg C /Estimated/