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Pyrazinamide

Pyrazinamide

Synonyms Pyrazinecarboxamide; Pyrazinoic acid amide

CAS Number: 98-96-4 Molecular Formula: C5H5N3O Molecular Weight: 123.115 g/mol

Beilstein Registry Number: 112306 EC Number: 202-717-6 MDL Number: MFCD00006132

SKU 02195473-CF
$47.65
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Description

Product Description

Pyrazinamide

Application Notes

Pyrazinamide is used therapeutically as an antitubercular agent. Pyrazinamide is used to form polymeric copper complexes, create pyrazine carboxamide scaffolds useful as FXs inhibitors, and as a component of mycobacteria identification kits. It is used to study liver toxicity prevention and mechanisms of resistance.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antitubercular agent

Specifications
SKU 02195473-CF
Alternate Names Pyrazinecarboxamide; Pyrazinoic acid amide
Application Notes Pyrazinamide is used therapeutically as an antitubercular agent. Pyrazinamide is used to form polymeric copper complexes, create pyrazine carboxamide scaffolds useful as FXs inhibitors, and as a component of mycobacteria identification kits. It is used to study liver toxicity prevention and mechanisms of resistance.
Base Catalog Number 195473
Beilstein Registry Number 112306
Biochemical Physiological Actions The active moiety of pyrazinamide is pyrazinoic acid (POA). POA is thought to disrupt membrane energetics and inhibit membrane transport function at acid pH in Mycobacterium tuberculosis. Iron enhances the antituberculous activity of pyrazinamide. Pyrazinamide and its analogs have been shown to inhibit the activity of purified FAS I.
Boiling Point SUB (NTP, 1992)
CAS # 98-96-4
EC Number 202-717-6
Format Powder
Melting Point 376 to 379° F (NTP, 1992)
Molecular Formula C5H5N3O
Molecular Weight 123.115 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
pH Aqueous solutions are neutral
Purity ≥99%
RTECS Number UQ2275000
Solubility >18.5 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.