Product lectin is pure Phytolacca americana from Pokeweed. Pure pokeweed mitogen is used in mitogenic assays. It has variety of applications in vitro like blood grouping and erythrocyte polyagglutination studies, mitogenic stimulation of lymphocytes, lymphocyte subpopulation studies, fractionation of cells and other particles, histochemical studies of normal and pathological conditions. Pokeweed mitogen has specificity for sugar chains containing a di-N-Acetylchitobiose moiety such as is found on "band-3 glycoprotein" from human erythrocytes. Di-N-acetylchitobiose and tri-N-acetylchitobiose inhibit agglutination activity of the lectin.
Application Notes
Pure pokeweed mitogen is used in mitogenic assays. It has variety of applications in vitro like blood grouping and erythrocyte polyagglutination studies, mitogenic stimulation of lymphocytes, lymphocyte subpopulation studies, fractionation of cells and other particles, histochemical studies of normal and pathological conditions.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Immunoassays | Mitogenic assay
| SKU | 08780341 |
| Alternate Names | PWM; Pokeweed mitogen; Lectin from Phytolacca americana(pokeweed) |
| Application Notes | Pure pokeweed mitogen is used in mitogenic assays. It has variety of applications in vitro like blood grouping and erythrocyte polyagglutination studies, mitogenic stimulation of lymphocytes, lymphocyte subpopulation studies, fractionation of cells and other particles, histochemical studies of normal and pathological conditions. |
| Base Catalog Number | 780341 |
| Formulation Details | Lyophilized |
| Molecular Weight | 32 kDa (sedimentation equilbrium) (Lit.) |
| Pack Size | 1 mg |
| Protein or Enzyme Type | Other Proteins, Enzymes Peptides |
| Solubility | Soluble in phosphate buffered saline (1 mg/mL). |
| Source | Phytolacca americana(pokeweed) |
| Specific Activity | Less than 0.5 mg/mL will agglutinate neuraminidase treated human red blood cells. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
![MP COA [78034] lot ID: Q1800](https://www.mpbio.com/static/version1781680552/frontend/Mpbio/luma/en_US/images/document.png "MP COA [78034] lot ID: Q1800")
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