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Polymyxin B sulfate, Cell Culture Reagent

Polymyxin B sulfate, Cell Culture Reagent

Synonyms Aerosporin

CAS Number: 1405-20-5 Molecular Formula: C55H96N16O13·2H2SO4 Molecular Weight: 1301.571 g/mol

EC Number: 215-774-7 MDL Number: MFCD00131991

SKU 02194538-CF
$39.30
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Description

Product Description

Polymyxin B Sulfate

Application Notes

It is used as a lipid A binding agent that induces pore formation in cell membranes and as immobilized (substrate bound) agent for removal of endotoxins. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa. It also has uses studying multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02194538-CF
Alternate Names Aerosporin
Application Notes It is used as a lipid A binding agent that induces pore formation in cell membranes and as immobilized (substrate bound) agent for removal of endotoxins. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa. It also has uses studying multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.
Base Catalog Number 194538
Biochemical Physiological Actions Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mode of Action: Binds to and interferes with the permeability of the cytoplasmic membrane. Antimicrobial spectrum: Gram-negative bacteria.
CAS # 1405-20-5
EC Number 215-774-7
Format Powder
Grade Cell Culture Grade
Hazard Statements H302
Molecular Formula C55H96N16O13·2H2SO4
Molecular Weight 1301.571 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Gloves
Potency >6,000 u/mg
RTECS Number TR1150000
Safety Symbol GHS07
Solubility Water Solubility25 mg/mL
Typical Working Concentration 50 mg/L
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.