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Polymyxin B sulfate

Polymyxin B sulfate

Synonyms Aerosporin

CAS Number: 1405-20-5 Molecular Formula: C55H96N16O13·2H2SO4 Molecular Weight: 1301.571 g/mol

EC Number: 215-774-7 MDL Number: MFCD00131991

SKU 02100565-CF
$43.90
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Description

Product Description

Polymyxin B Sulfate

Application Notes

Polymyxin B sulfate is a mixture of Polymyxin B1 and B2 sulfate. It is used clinically to treat infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa. It is used to study multidrug-resistant pathogens.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Cell culture

Specifications
SKU 02100565-CF
Alternate Names Aerosporin
Application Notes Polymyxin B sulfate is a mixture of Polymyxin B1 and B2 sulfate. It is used clinically to treat infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa. It is used to study multidrug-resistant pathogens.
Base Catalog Number 100565
Biochemical Physiological Actions Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides†, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.Antimicrobial spectrum: Has bactericidal action on most gram-negative bacilli††, including E. Coli and on most fungi and gram-positive bacteria.
CAS # 1405-20-5
EC Number 215-774-7
Format Powder
Hazard Statements H302
Molecular Formula C55H96N16O13·2H2SO4
Molecular Weight 1301.571 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pKa 43227
RTECS Number TR1150000
Solubility Water Solubility25 mg/mL
Source Soluble in water; 1 mM HCl
Unit Definition Effective concentration is typically 50 mg/L.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.