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Penicillin G, sodium salt, USP phytopure™

Penicillin G, sodium salt, USP phytopure™

Synonyms Benzylpenicillin sodium salt

CAS Number: 69-57-8 Molecular Formula: C16H17N2O4Sna Molecular Weight: 356.40

Beilstein Registry Number: 3834217 EC Number: 200-710-2 MDL Number: MFCD00069666

SKU 02194537-CF
$53.15
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Description

Product Description

A semi-synthetic, broad-spectrum β-lactam penicillin antibiotic with bactericidal activity against gram-positive bacteria. It inhibits bacterial cell wall synthesis by disrupting peptidylglycan cross-linking.

Application Notes

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02194537-CF
Alternate Names Benzylpenicillin sodium salt
Application Notes Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.
Base Catalog Number 194537
Beilstein Registry Number 3834217
Biochemical Physiological Actions Mode of Action: The β-lactam moiety (functional group) of penicillin G binds to the enzyme (DD-transpeptidase) that links the peptidoglycan molecules in bacteria. The enzymes that hydrolyze the peptidoglycan cross-links continue to function, which weakens the cell wall of the bacterium, it causes cytolysis(death due to osmotic pressure) in Bactria. Antimicrobial spectrum: Gram-positive bacteria.
CAS # 69-57-8
Density 1.41 (NTP, 1992)
EC Number 200-710-2
Format Powder
Grade USP
Hazard Statements H317-H334
Melting Point 408 to 414° F (decomposes) (NTP, 1992)
Molecular Formula C16H17N2O4Sna
Molecular Weight 356.40
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Potency >1500 u/mg
RTECS Number XH9800000
Safety Symbol GHS08
Solubility 50 to 100 mg/mL at 77° F (NTP, 1992)
Sterilization of Solutions Solutions should be filter sterilized. Store in small aliquots at appropriate temperature until use.
Typical Working Concentration For Gram Positive Bacteria=105 U/L
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.