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Paromomycin sulfate

Paromomycin sulfate

Synonyms Paromomycin sulfate salt

CAS Number: 1263-89-4 Molecular Formula: C23H45N5O14·×H2SO4·×H2O Molecular Weight: 713.706 g/mol

Beilstein Registry Number: 5715182 EC Number: 215-031-7 MDL Number: MFCD00079278

SKU 02156056-CF
$76.45
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Description

Product Description

Paromomycin Sulfate

Application Notes

Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against Gram-negative bacteria, Gram-positive bacteria, some protozoan species, and limited antihelminth.It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules and is used to inhibit Cryptosporidium infection of a human enterocyte cell line.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02156056-CF
Alternate Names Paromomycin sulfate salt
Application Notes Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against Gram-negative bacteria, Gram-positive bacteria, some protozoan species, and limited antihelminth.It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules and is used to inhibit Cryptosporidium infection of a human enterocyte cell line.
Base Catalog Number 156056
Beilstein Registry Number 5715182
Biochemical Physiological Actions Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.
CAS # 1263-89-4
EC Number 215-031-7
Format Powder
Molecular Formula C23H45N5O14·×H2SO4·×H2O
Molecular Weight 713.706 g/mol
Potency >675 µg/mg
Purity >97%
RTECS Number WK2320000
Typical Working Concentration 100 mg/L
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.