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Minocycline is active against streptococci,enterobacteria, and some mycobacteria, and also against such species as Staphylococcus aureus, Neisseria meningitidis, Acinetobacter, Bacteroides, Haemophilus, and Nocardia.
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Antibacterial | Antibiotics
|Alternate Names||[4S-(4α,4aα5,5aα,12aα)]- 4,7-bis(dimethylamino)-14,4a,5,5a,6,11,12aoctahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; 7-dimethylamino- 6-demethyl-6-deoxytetracycline|
|Application Notes||Minocycline is active against streptococci,enterobacteria, and some mycobacteria, and also against such species as Staphylococcus aureus, Neisseria meningitidis, Acinetobacter, Bacteroides, Haemophilus, and Nocardia.|
|Base Catalog Number||155718|
|Biochemical Physiological Actions||Minocycline inhibits endothelial cell proliferation and angiogenesis.|
|Molecular Formula||C23H27N3O7 • HCl|
|Molecular Weight||493.941 g/mol|
|Personal Protective Equipment||Dust mask, Eyeshields, Faceshields, Gloves|
|Solubility||In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 52,000 mg/l at 25 deg C.|
|Typical Working Concentration||Minimum inhibitory concentrations (MIC) can range from 0.06 - 1 µg/mL for the most sensitive organisms, and from 4 - 12.5 µg/mL for moderately sensitive organisms.|