Phytohemagglutinin

Name: Phytohemagglutinin
SKU: 02151884-CF
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SKU: 02151884-CF

Key features and details

Phytohemagglutinin

Synonyms

PHA

CAS Number:

9008-97-3

EC Number:

232-718-7

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Product Description

Phytohemagglutinin

Application Notes

In medicine PHA proteins are useful and are used as a mitogen to trigger T-lymphocytes cell division and to activate latent HIV-1 from human peripheral lymphocytes.The lectin has a number of effects on cell metabolism; it induces mitosis, and affects the cell membrane in regard to transport and permeability to proteins. It is used as positive control in ELIspot assay.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Agglutination

Specifications

SKU	02151884-CF
Alternate Names	PHA
Application Notes	In medicine PHA proteins are useful and are used as a mitogen to trigger T-lymphocytes cell division and to activate latent HIV-1 from human peripheral lymphocytes.The lectin has a number of effects on cell metabolism; it induces mitosis, and affects the cell membrane in regard to transport and permeability to proteins. It is used as positive control in ELIspot assay.
Base Catalog Number	151884
Biochemical Physiological Actions	PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity. PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides. PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin. PHA-M is the mucoprotein form. Conjugates are prepared from the corresponding purified lectins.
CAS #	9008-97-3
EC Number	232-718-7
Format	Off-white Lyophilized Powder
Protein or Enzyme Type	Lectins
RTECS Number	TJ3470000
Source	Red Kidney Beans (Phaseolus vulgaris)
Specific Activity	Shows agglutination when tested with human red blood cells.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.