Product Description
MP Biomedicals CD81 Rabbit Monoclonal Antibody offers high specificity and potency and consistency against human/mouse/rat CD81 (a classical exosome biomarker involved in cancer cells metastasis), which has been experimentally validated in WB assay.
Usage Statement
Research use only, not for direct human use.
Key Applications
WB
Specifications
| SKU | 08L100022 |
| Alternate Names | CD81; CVID6; S5.7; TAPA1; TSPAN28 |
| Antibody Type | Monoclonal Antibody |
| Background_information | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also, it may be involved in signal transduction. This gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. |
| Bioreactivity | High specificity against CD81 antigen has been experimentally validated. |
| Concentration | Please check the vial’s label |
| Conjugate | Unconjugated |
| Formulation Details | In PBS buffer with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3-7.4. This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. This antibody is stable for twelve months from the date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Grade | Molecular Grade |
| Host | Rabbit |
| Immunogen | With a proprietary peptide derived from the C-terminal sequence of human CD81 protein as an immunogen. |
| Isotype | Rabbit IgG |
| Molecular Weight | Observed at 22 kDa |
| Pack Size | 100 µL |
| Preparation Method | Affinity purification |
| Solubility | Dissolves in Tris or PBS buffer immediately |
| Species Reactivity | Human, Mouse, Rat |
| Storage | -20° |
| Typical Working Concentration | WB: 1:500 to 1:2,000 . |
| Uniprot Number | P60033 |
| Usage Statement | Research use only, not for direct human use. |
Documents
Certificate of Analysis (COA)
Datasheet
Datasheet
English (United States)
Safety Data Sheets
English (United States)
Brochures
Brochures
English (United States)
Brochures
English (United States)
Brochures
English (United States)