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Hyaluronidase from steotomyces hyalurolyticus, ~2000 U/mg
Hyaluronidase is used to increase the absorption and dispersion of injected drugs or to disrupt the structure of certain organs.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
|Alternate Names||E.C. 220.127.116.11; Hyaluronate Glycanohydrolase; Hyaluronate lyase; Mucinase; EC 18.104.22.168|
|Application Notes||Hyaluronidase is used to increase the absorption and dispersion of injected drugs or to disrupt the structure of certain organs.|
|Base Catalog Number||151270|
|Biochemical Physiological Actions||Hyaluronidase splits the N-acetylglucosaminic linkages in hyaluronic acid eliminatively, yielding Δ-4,5-unsaturated tetrasaccharides and hexasaccharides as the end-product.|
|Specific Activity||~2000 u/mg|
|Specificity||Hyaluronidase purified from Streptomyes hyalurolyticus is distinct from the known hyaluronidase in its substrate specificity and mechanism of action. This enzyme is quite specific for hyaluronic acid. Various types of chondroitin sulfate (A;B;C;D;;E); chondroitin; heparin; keratan sulfate and chitin are not attacked by this enzyme.|
|Unit Definition||Enzyme activity is determined by a change in optical density in a solution of hyaluronic acid. Activity is compared to a hyaluronidase International Standard and is expressed as an International Unit (U).|
|Usage Statement||Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.|