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Hyaluronidase, >1500 U/mg

Hyaluronidase, >1500 U/mg

Synonyms Hyaluronate 4-glycanohydrolase; hyaluronate lyase; hyaluronoglucosaminidase; 3.2.1.35

CAS Number: 37326-33-3

EC Number: 253-464-3 MDL Number: MFCD00131351

SKU 02151274-CF
$124.60
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Description

Product Description

Hyaluronidase

Application Notes

Testicular hyaluronidase hydrolyzes the endo-N-acetylhexosaminic bonds of hyaluronic acid and chondroitin sulfuric acids A and C (but not B), primarily to tetrasaccharide residues. Monosaccharides are not liberated. Hyaluronidase is often used in conjunction with collagenase to dissociate the extracellular matrix between cells of animal tissue, in order to release viable cells for use in tissue culture. It may also be used to clarify synovial fluids in order to make cell counts possible.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Drug dispersion & delivery

Specifications
SKU 02151274-CF
Alternate Names Hyaluronate 4-glycanohydrolase; hyaluronate lyase; hyaluronoglucosaminidase; 3.2.1.35
Application Notes Testicular hyaluronidase hydrolyzes the endo-N-acetylhexosaminic bonds of hyaluronic acid and chondroitin sulfuric acids A and C (but not B), primarily to tetrasaccharide residues. Monosaccharides are not liberated. Hyaluronidase is often used in conjunction with collagenase to dissociate the extracellular matrix between cells of animal tissue, in order to release viable cells for use in tissue culture. It may also be used to clarify synovial fluids in order to make cell counts possible.
Base Catalog Number 151274
Biochemical Physiological Actions Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression. These enzymes randomly cleave β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.
CAS # 37326-33-3
EC Number 253-464-3
Extinction Coefficient ~8
Format lyophilized, Salt free
Hazard Statements H317
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Source Ovine Testes
Specific Activity >1500 u/mg material
Specificity Testicular hyaluronidase hydrolyzes the endo-N-acetylhexosaminic bonds of hyaluronic acid and chondroitin sulfuric acids A and C (but not B); primarily to tetrasaccharide residues. Monosaccharides are not liberated.
Unit Definition Amount of enzyme which liberates one micromole of N-acetylglucosamine per minute at 37°C and pH 4.0
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.