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Flumequine, 25 g

Flumequine, 25 g

CAS Number: 42835-25-6 Molecular Formula: C14H12FNO3 Molecular Weight: 261.25

Beilstein Registry Number: 490724 EC Number: 255-962-6 MDL Number: MFCD00079298

Packaging size: 25 g

SKU 0215805625
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SKU 0215805625
Application Notes Flumequine is a fluoroquinolone synthetic chemotherapeutic antibiotic. Flumequine is used to study processes that affect mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases. It is used to study hepatocarcinogenicity and DNA damage in mice and the mechanisms of quinolone resistance.
Base Catalog Number 15805625
Beilstein Registry Number 490724
Biochemical Physiological Actions Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .
CAS # 42835-25-6
EC Number 255-962-6
Melting Point 253-255 °C (Lit.)
Molecular Formula C14H12FNO3
Molecular Weight 261.25
Pack Size 25 g
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Solubility Practically insoluble in water, slightly soluble in ethanol, in methanol, acetone and in chloroform, insoluble in benzene, soluble in alkaline solution, soluble in 1M ammonium hydroxide (200 mg/ 4 mL-clear faint yellow solution).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.