20 Years of FastPrep^® Built for Tough Samples Save 20% — or 30% with an instrument

Researchers studying influenza A found that TLR3—an immune sensor designed to detect viral infection—could also contribute to damaging lung inflammation. Mice lacking TLR3 carried more virus but survived infection better, showing that the immune response itself can sometimes become part of the problem.

Lung tissue RNA used for RT-PCR was extracted with the FastRNA GREEN Kit and a FastPrep instrument.

In a first-in-human trial, researchers delivered siRNA in targeted nanoparticles and obtained direct evidence that RNA interference was working inside patients’ tumor cells.

Patient tumor biopsies used for RNA analysis were homogenized with a FastPrep-24.

Researchers recovered microbial RNA from deep subseafloor sediments and produced the first metatranscriptomes from this environment, revealing active metabolism and cell division far below the ocean floor.

FastRNA Pro Soil-Direct, Lysing Matrix E and FastPrep-24 were used to extract RNA from the low-biomass sediment.

DNA from sediment near the Loki’s Castle hydrothermal field revealed Lokiarchaeota, a previously unknown group of archaea whose genes helped reshape ideas about the evolutionary origins of complex eukaryotic cells.

DNA from deep-sea sediment was extracted using the FastDNA Spin Kit for Soil together with FastPrep-24.

Researchers discovered that some bacteriophages release a communication peptide and use the accumulated signal to help decide whether to kill their bacterial host immediately or remain dormant inside it.

Lysing Matrix B + FastPrep-24 supported ChIP-seq lysis, and FastPrep was also used in the RNA-seq workflow.

Cyanobacteria are best known for harvesting light, yet researchers found cyanobacteria-dominated communities deep inside subsurface rock and evidence that they may survive using light-independent metabolism.

Powdered subsurface rock underwent repeated FastPrep bead-beating cycles during DNA extraction for metagenomic analysis.

The team developed a microbial-enrichment method that reduced overwhelming host DNA by more than 1,000-fold, making detailed metagenomics possible directly from intestinal biopsies.

Lysing Matrix D + FastPrep-24 were built directly into the microbial-enrichment and microbial DNA extraction workflow.

Researchers found that sucralose altered the gut microbiome, reduced microbiota-accessible arginine and impaired T-cell function in preclinical models, with an association also observed in patients receiving immune-checkpoint therapy.

Tumor samples used for metabolomic measurements were homogenized with an MP Bio FastPrep system and Matrix D.

The Sanger Tree of Life programme has released chromosome-scale reference genomes for more than 2,000 species while developing standardized workflows for thousands of wildly different organisms.

FastPrep-96 is used at scale for tissue disruption, including up to 96 samples in parallel and difficult plant and coral material.

Portable sequencing was already possible, but DNA extraction still depended on laboratory equipment. Researchers built a field-deployable quantitative metagenomics workflow for environmental and water samples that moved sample preparation closer to the point of collection.

SuperFastPrep-2 replaced a benchtop homogenizer in the portable DNA-extraction workflow, enabling rapid bead beating outside a conventional lab while producing DNA suitable for long-read Nanopore sequencing.