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Erythromycin, cell culture reagent, ~98%, 5 g

Erythromycin, cell culture reagent, ~98%, 5 g

Synonyms E- mycin; Erycin; Robimysin; Erythrocin

CAS Number: 114-07-8 Molecular Formula: C37H67NO13 Molecular Weight: 733.95

Beilstein Registry Number: 75279 EC Number: 204-040-1 MDL Number: MFCD00084654

Packaging size: 5 g

SKU 0219452905
$55.20
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Description

Product Description

Erythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis. This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus. It is a mixture consisting largely of erythromycin A with lesser amounts of erythromycins B and C.

Application Notes

Used in cell culture applications at approximately 100 mg/liter. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 0219452905
Alternate Names E- mycin; Erycin; Robimysin; Erythrocin
Application Notes Used in cell culture applications at approximately 100 mg/liter. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria.
Base Catalog Number 19452905
Beilstein Registry Number 75279
Biochemical Physiological Actions Mode of Action: Inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site). Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
CAS # 114-07-8
EC Number 204-040-1
Extinction Coefficient EM = 50 (280 nm, pH 6.3)
Grade Cell Culture Grade
Melting Point 135 to 140 °C (Lit.)
Molecular Formula C37H67NO13
Molecular Weight 733.95
Optical Rotation -71° to -78° (c=2, ethanol)
Pack Size 5 g
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pH 8.0 - 10.5 (70% aq soln)
pKa 8.8
Potency ≥850 ug/mg
Purity 98%
RTECS Number KF4375000
Solubility Slightly soluble in water (~2 mg/mL); Moderately soluble in ether, ethylene dichloride, amyl acetate; freely soluble in alcohols (ethanol - 50 mg/mL), acetone, chloroform, acetonitrile, ethyl acetate. Soluble in 2 M Hydrochloric acid (50 mg/mL).
Typical Working Concentration Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.