Coomassie Brilliant Blue G-250, 10 g
SKU: 04808274
Coomassie® Brilliant Blue G-250
Application Notes
Brilliant Blue G is a useful dye for SDS gels as it readily stains proteins with minimal background color. Protein bands can be visualized during staining. It has been used in the Bradford dye-binding protein assay. A mechanism for dye binding to protein has been proposed, based onmeasuring Coomassie Brilliant Blue G-250 (CBBG) absorbance spectra during titration of the dye reagent in the absence of protein and its response to different polyamino acids. Brilliant Blue G has been used for determining critical micelle concentration of detergents. Recent research reveals CBBG as a P2X7 (P2X purinoceptor 7: P2RX7) antagonist and suggests that it exhibits neuroprotective properties in rat spinal cord cells.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Cell Biology | Hematology | Protein staining
| SKU | 04808274 |
| Alternate Names | Brilliant Blue G; C.I. 42655; Acid Blue 90; Coomassie Brilliant Blue G; CBBG |
| Application Notes | Brilliant Blue G is a useful dye for SDS gels as it readily stains proteins with minimal background color. Protein bands can be visualized during staining. It has been used in the Bradford dye-binding protein assay. A mechanism for dye binding to protein has been proposed, based onmeasuring Coomassie Brilliant Blue G-250 (CBBG) absorbance spectra during titration of the dye reagent in the absence of protein and its response to different polyamino acids. Brilliant Blue G has been used for determining critical micelle concentration of detergents. Recent research reveals CBBG as a P2X7 (P2X purinoceptor 7: P2RX7) antagonist and suggests that it exhibits neuroprotective properties in rat spinal cord cells. |
| Base Catalog Number | 808274 |
| Beilstein Registry Number | 5230822 |
| Biochemical Physiological Actions | P2X7 purinergic receptor antagonist. |
| CAS # | 6104-58-1 |
| Color Index | 42655 |
| EC Number | 228-058-4 |
| Format | Powder |
| Grade | Electrophoresis grade |
| Molecular Formula | C47H48N3O7S2Na |
| Molecular Weight | 854.025 g/mol |
| Pack Size | 10 g |
| Personal Protective Equipment | Eyeshields, Gloves, Respirator filter |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | 610 - 619 nm (50% ethanol) |
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