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Cefotaxime, sodium salt, phytopure™

Cefotaxime, sodium salt, phytopure™

Synonyms Cefotaxime sodium; (6R-(6-a,7-b(Z)))-3-((Acetyloxy) methyl)-7- (((2-amino-4-thiazolyl) (methoxyimio) acetyl) amino)-8- oxo-5-thia-1- azabicyclo (4,2,0) oct-2-ene-2-carboxylic acid, sodium salt

CAS Number: 64485-93-4 Molecular Formula: C16H16N5O7S2Na Molecular Weight: 477.40

Beilstein Registry Number: 5711411 EC Number: 264-915-9 MDL Number: MFCD00079073

SKU 02154947-CF
$44.85
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Description

Product Description

A cephalosporin antibiotic effective against gram-positive and gram-negative bacteria. It interferes with cell wall formation by inhibiting cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell walls. Useful in plant cell culture because it doesn't affect the plasmids of developed vascular plants.

Application Notes

Cefotaxime is used for infections of the respiratory tract, skin, bones, joints, urogenital system, meninges, and bloodstream. It generally has good coverage against most Gram-negative bacteria, with the notable exception of Pseudomonas. It is also effective against most Gram-positive cocci except for Enterococcus. It is active against penicillin-resistant strains of Streptococcus pneumoniae. It has modest activity against the anaerobic Bacteroides fragilis. In meningitis, cefotaxime crosses the blood–brain barrier better than cefuroxime.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Cell wall inhibitor

Specifications
SKU 02154947-CF
Alternate Names Cefotaxime sodium; (6R-(6-a,7-b(Z)))-3-((Acetyloxy) methyl)-7- (((2-amino-4-thiazolyl) (methoxyimio) acetyl) amino)-8- oxo-5-thia-1- azabicyclo (4,2,0) oct-2-ene-2-carboxylic acid, sodium salt
Application Notes Cefotaxime is used for infections of the respiratory tract, skin, bones, joints, urogenital system, meninges, and bloodstream. It generally has good coverage against most Gram-negative bacteria, with the notable exception of Pseudomonas. It is also effective against most Gram-positive cocci except for Enterococcus. It is active against penicillin-resistant strains of Streptococcus pneumoniae. It has modest activity against the anaerobic Bacteroides fragilis. In meningitis, cefotaxime crosses the blood–brain barrier better than cefuroxime.
Base Catalog Number 154947
Beilstein Registry Number 5711411
Biochemical Physiological Actions Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
CAS # 64485-93-4
EC Number 264-915-9
Hazard Statements H317-H334
Molecular Formula C16H16N5O7S2Na
Molecular Weight 477.40
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Purity ≥95%
RTECS Number XI0250000
Safety Symbol GHS08
Solubility 68.2 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.