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Caerulein, sulfated

Caerulein, sulfated

$371.00
Caerulein, Sulfated

SKU: 02152860-CF

Synonyms
pyroGlu-Gln-Asp-Tyr[SO3H]-Thr- Gly-Trp-Met-Asp-Phe-NH2; Caerulein Sulfated; Cerulein; Ceruletide; [Tyr(SO3H)4]Caerulein
CAS Number:
17650-98-5
Molecular Formula:
C58H73N13O21S2
Molecular Weight:
1352.412 g/mol
Beilstein Registry Number:
5422487
MDL Number:
MFCD00076478
Product Description

Caerulein, Sulfated

Application Notes

Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer

Specifications
SKU 02152860-CF
Alternate Names pyroGlu-Gln-Asp-Tyr[SO3H]-Thr- Gly-Trp-Met-Asp-Phe-NH2; Caerulein Sulfated; Cerulein; Ceruletide; [Tyr(SO3H)4]Caerulein
Application Notes Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication.
Base Catalog Number 152860
Beilstein Registry Number 5422487
Biochemical Physiological Actions It is seen as an antagonist of endogenous opioids.
CAS # 17650-98-5
Format Powder
Molecular Formula C58H73N13O21S2
Molecular Weight 1352.412 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Preparation Method The peptide is to be dissolved in distilled, oxygen free or preferable sterile oxygen free water first. The concentration should be high enough to allow addition of buffer after the products is dissolved completely. If necessary diluted acetic acid or ammonium hydroxide, app. 1%, can be added to help solubilize the peptide. In those rare cases where solubilization is still not achieved, the solution may be sonicated briefly (up to 10 min, temperature shouldn't rise over 30-40 °C). In order to avoid serious solubility problems, buffer or saline should be added after the peptide is fully in solution.
Solubility 1.16e-02 g/L
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

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