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Bupivacaine hydrochloride

Product Description

Bupivacaine Hydrochloride

Application Notes

Bupivacaine is used as a long-acting local anesthetic. It is used mainly for infiltration and regional nerveblocks, but is not recommended for topical anesthesia.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Local anesthetic

Specifications

SKU	02154904-CF
Alternate Names	1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
Application Notes	Bupivacaine is used as a long-acting local anesthetic. It is used mainly for infiltration and regional nerveblocks, but is not recommended for topical anesthesia.
Base Catalog Number	154904
Biochemical Physiological Actions	Bupivacaine is a sodium channel blocker, local anesthetic. It binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Since pain transmitting nerve fibres tend to be thinner and either unmyelinated or lightly myelinated, the agent can diffuse more readily into them than into thicker and more heavily myelinated nerve fibres like touch, proprioception, etc. (Myelin is non-polar / lipophilic). It should be noted, however, that bupivacaine also blocks specific potassium channels, an effect contributing to resting membrane potential depolarization.
CAS #	14252-80-3
EC Number	241-917-8
Hazard Statements	H300-H310-H330
Molecular Formula	C18H28N2O · HCl
Molecular Weight	324.893 g/mol
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
RTECS Number	TK6125000
Safety Symbol	GHS06
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.