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Aprotinin

Aprotinin

Synonyms Pancreatic Basic Trypsin Inhibitor, polypeptide; Antagosan; Antikrein; Trasylol; Zymofren; Trypsin inhibitor (basic); Antilysin(e); BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Triazinin

CAS Number: 9087-70-1 Molecular Formula: C284H432N84O79S7 Molecular Weight: 6511.509 g/mol

EC Number: 232-994-9 MDL Number: MFCD00130541

SKU 02194559-CF
$145.65
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Description

Product Description

Aprotinin

Application Notes

It is used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Serine protease inhibitor

Specifications
SKU 02194559-CF
Alternate Names Pancreatic Basic Trypsin Inhibitor, polypeptide; Antagosan; Antikrein; Trasylol; Zymofren; Trypsin inhibitor (basic); Antilysin(e); BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Triazinin
Application Notes It is used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones.
Base Catalog Number 194559
Biochemical Physiological Actions Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3.
CAS # 9087-70-1
EC Number 232-994-9
Extinction Coefficient E1% (280 nm) = 8.3 (water)(Lit.)
Format Powder
Grade Cell Culture Grade
Isoelectric Point 10.5(Lit.)
Melting Point >100 °C
Molecular Formula C284H432N84O79S7
Molecular Weight 6511.509 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
RTECS Number YN5080000
Source Bovine Lung
Specific Activity ~4 inhibitor u/mg
Sterilization of Solutions Sterilization of solutions can be done by filtration through a 0.2 µm filter.
Typical Working Concentration Effective Concentration is Equimolar with protease (1-2 µg/mL).
Unit Definition One Kallikrein Inactivating Unit is the quantity of protease inhibitor that has the ability to inhibit 2 Kallikrein units by 50% under optimal conditions.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max (water) : 277 ± 5 nm