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Ampicillin (gamma irradiated), molecular biology grade, 20 mg

Ampicillin (gamma irradiated), molecular biology grade, 20 mg

Synonyms D[-]-α-Aminobenzylpenicillin; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid; D-(−)-α-Aminobenzylpenicillin sodium salt; Aminobenzylpenicillin sodium salt

CAS Number: 69-52-3 Molecular Formula: C16H18N3NaO4S Molecular Weight: 371.39

Beilstein Registry Number: 4119211 EC Number: 200-708-1 MDL Number: MFCD00064313

Packaging size: 20 mg

SKU 0219419920
$32.10
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Description

Product Description

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic.It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as benzylpenicillin; against gram-negative bacteria, it has a similar mode of action as chloramphenicol and tetracyclines. In E. coli it inhibits cell wall synthesis.

Application Notes

Ampicillin sodium salt is used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 0219419920
Alternate Names D[-]-α-Aminobenzylpenicillin; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid; D-(−)-α-Aminobenzylpenicillin sodium salt; Aminobenzylpenicillin sodium salt
Application Notes Ampicillin sodium salt is used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.
Base Catalog Number 19419920
Beilstein Registry Number 4119211
Biochemical Physiological Actions A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing <i>Escherichia coli</i>. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
CAS # 69-52-3
EC Number 200-708-1
Grade Molecular Biology Grade
Hazard Statements H317-H334
Melting Point 215 °C decomposes (Lit.)
Molecular Formula C16H18N3NaO4S
Molecular Weight 371.39
Pack Size 20 mg
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
pH 8 - 10 (1% aq soln)
pKa At 25 °C ,pKa = 2.5 (-COOH),pKa = 7.3 (-NH<sub>2</sub>) (Lit.)
Potency ≥800 ug/mg
RTECS Number XH8400000
Safety Symbol GHS08
Solubility Soluble in water (50 mg/mL); soluble in 1 M Ammonium Hydroxide, dilute acids or bases; practically insoluble in alcohol, chloroform, ether and fixed oils.
Typical Working Concentration 100 mg/liter for both gram positive and gram negative bacteria
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.