Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other fungi. Amphotericin B may be toxic to some insect cell types. Amphotericin B, is an antimycotic.
Amphotericin B is used as antifungal in cell culture media.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Cell culture applications | Antimicrobial Treatment
|Application Notes||Amphotericin B is used as antifungal in cell culture media.|
|Base Catalog Number||1672346,1672348|
|Formulation Details||Liquid | It is formulated with deoxycholate and prepared in water for increased solubility.|
|Solubility||Slightly soluble in water; DMF/1M HCL 3/1: 49.00 - 51.00 mg/mL; Amphotericin B is insoluble in water at pH 6 to 7, but soluble in water at pH 2 or 11. It is soluble in DMSO (30 – 40 mg/mL) and in dimethylformamide (2 – 4 mg/mL).|
|Typical Working Concentration||0.25 – 2.5 μg/mL|
|Usage Statement||Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.|