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5-Iodo-2'-deoxyuridine (5-IUdR; IdUrd) is a pyrimidine analog (halogenated thymidine) that has antiviral activity agains vaccinia virus (orthopoxviruses). IdUrd is used as a radiosensitizer in human cancer studies.
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Antiviral agent | Radiosensitizer
|Alternate Names||1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil; 2'-Deoxy-5-iodouridine; 5-IUdR; IDU; IdUrd; Idoxuridine|
|Application Notes||5-Iodo-2'-deoxyuridine (5-IUdR; IdUrd) is a pyrimidine analog (halogenated thymidine) that has antiviral activity agains vaccinia virus (orthopoxviruses). IdUrd is used as a radiosensitizer in human cancer studies.|
|Base Catalog Number||100357|
|Beilstein Registry Number||30397|
|Molecular Weight||354.1 g/mol|
|Optical Rotation||+28° to +37° (C=1, 1 N NaOH)|
|Personal Protective Equipment||Eyeshields, Faceshields, Gloves, respirator cartridges|
|pH||pH of 0.1% aqueous soln, about 6|
|Safety Symbol||GHS07, GHS08|
|Solubility||Water Solubility2000 mg/L (at 25 °C)|