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5-Fluorodeoxyuridine

5-Fluorodeoxyuridine

$34.35
5-Fluorodeoxyuridine

SKU: 02105551-CF

Synonyms
2'-Deoxy-5-Fluorouridine; Floxuridine; 5-Fluoro-2'-deoxyuridine; FUDR; dFUR
CAS Number:
50-91-9
Molecular Formula:
C9H11FN2O5
Molecular Weight:
246.194 g/mol
Beilstein Registry Number:
90221
EC Number:
200-072-5
MDL Number:
MFCD00006530
Product Description

5-Fluorodeoxyuridine

Application Notes

5-Fluorodeoxyuridine can be used to target thymidylate synthetase in cancer chemotherapy. Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chemotherapy

Specifications
SKU 02105551-CF
Alternate Names 2'-Deoxy-5-Fluorouridine; Floxuridine; 5-Fluoro-2'-deoxyuridine; FUDR; dFUR
Application Notes 5-Fluorodeoxyuridine can be used to target thymidylate synthetase in cancer chemotherapy. Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.
Base Catalog Number 105551
Beilstein Registry Number 90221
Biochemical Physiological Actions Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase. Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.
CAS # 50-91-9
EC Number 200-072-5
Extinction Coefficient EmM = 8.91 (0.1 M phosphate buffer, pH 6.0) (Lit.)
Format Powder
Hazard Statements H301
Melting Point 302 to 304° F (NTP, 1992)
Molecular Formula C9H11FN2O5
Molecular Weight 246.194 g/mol
Optical Rotation +37 ° (10 mg/mL in water at 25 °C) (Lit.)
Personal Protective Equipment Dust mask , Eyeshields, Faceshields, Gloves
pKa 7.6 (Lit.)
Purity >98%
RTECS Number YU7525000
Safety Symbol GHS06
Solubility Water Solubility11900 mg/L
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λmax (water) : 266 - 270 nm
Vapor Pressure 7.6X10-13 mm Hg at 25 deg C (est)
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