5-Bromo-2′-Deoxyuridine
Application Notes
5-Bromo-2'-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Cell signaling | To label dividing cells | To study processes that induce cell proliferation
SKU | 02100171-CF |
Alternate Names | 5-BrdU; 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil; 5-Bromouracil deoxyriboside; BUdR |
Application Notes | 5-Bromo-2'-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation. |
Base Catalog Number | 100171 |
Beilstein Registry Number | 30395 |
Biochemical Physiological Actions | Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase. |
CAS # | 59-14-3 |
EC Number | 200-415-9 |
Format | Powder |
Hazard Statements | H340+H361 |
Melting Point | 365 to 369° F (NTP, 1992) |
Molecular Formula | C9H11BrN2O5 |
Molecular Weight | 307.1 g/mol |
Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
Purity | ≥99% |
RTECS Number | YU7350000 |
Safety Symbol | GHS08 |
Solubility | 10 to 50 mg/mL at 72° F (NTP, 1992) |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
UV Visible Absorbance | λ max (water): 279 ± 2, 209 ± 3 nm |
Vapor Pressure | 1.7X10-14 mm Hg at 25 deg C (est) |