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17α-Hydroxyprogesterone Double Antibody RIA Kit
The 17αOHP Double Antibody RIA Kit is intended for the measurement of 17α-hydroxyprogesterone in unextracted serum or plasma of adults and children. The steroid 17α-hydroxyprogesterone (17αOHP) is produced by both the adrenal cortex and gonads. Even though 17αOHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17αOHP, measurement of 17αOHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17αOHP is secreted in abundant excess. It is moderately elevated in the 11-b-hydroxylase deficiency as well. Measurement of 17αOHP is therefore valuable in the initial diagnosis of CAH.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
|Analyte / Target||17OHP (17 alpha hydroxyprogesterone)|
|Base Catalog Number||171102|
|Pack Size||100 Tubes|
|Sample Type||Plasma, Serum|
|Sample Volume||25 uL|
|Usage Statement||Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.|