TSG101/VPS23 Rabbit Monoclonal Antibody
$432.48
In stock
SKU: 08L100024
Product Description
MP Biomedicals TSG101/VPS23 Rabbit Monoclonal Antibody offers high specificity and potency and consistency against human/rat TSG101/VPS23 (a classical exosome biomarker involved in cancer cells metastasis), which has been experimentally validated in WB assay.
Usage Statement
Research use only, not for direct human use.
Key Applications
WB
Specifications
| SKU | 08L100024 |
| Alternate Names | TSG10; VPS23; TSG101 / VPS23; TSG101 |
| Antibody Type | Monoclonal Antibody |
| Background_information | The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for the maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. |
| Bioreactivity | High specificity against TSG101/VPS23 antigen has been experimentally validated. |
| Concentration | Please check the vial’s label |
| Conjugate | Unconjugated |
| Formulation Details | In PBS buffer with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3-7.4. This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. This antibody is stable for twelve months from the date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Grade | Molecular Grade |
| Host | Rabbit |
| Immunogen | With a proprietary peptide derived from the N-terminal sequence of human TSG101/VPS23 protein as an immunogen. |
| Molecular Weight | Observed at 44 kDa |
| Pack Size | 100 µL |
| Preparation Method | Affinity purification |
| Solubility | Dissolves in Tris or PBS buffer immediately |
| Species Reactivity | Human, Rat |
| Storage | -20° |
| Typical Working Concentration | WB: 1:500 to 1:2,000 |
| Uniprot Number | Q99816 |
| Usage Statement | Research use only, not for direct human use. |
Documents
Certificate of Analysis (COA)
Datasheet
Datasheet
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Safety Data Sheets
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