Penicillin G Sodium Salt, cell culture grade
SKU: 02194537-CF
A semi-synthetic, broad-spectrum β-lactam penicillin antibiotic with bactericidal activity against gram-positive bacteria. It inhibits bacterial cell wall synthesis by disrupting peptidylglycan cross-linking.
Application Notes
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
| SKU | 02194537-CF |
| Alternate Names | Benzylpenicillin sodium salt |
| Application Notes | Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics. |
| Base Catalog Number | 194537 |
| Beilstein Registry Number | 3834217 |
| Biochemical Physiological Actions | Mode of Action: The β-lactam moiety (functional group) of penicillin G binds to the enzyme (DD-transpeptidase) that links the peptidoglycan molecules in bacteria. The enzymes that hydrolyze the peptidoglycan cross-links continue to function, which weakens the cell wall of the bacterium, it causes cytolysis(death due to osmotic pressure) in Bactria. Antimicrobial spectrum: Gram-positive bacteria. |
| CAS # | 69-57-8 |
| Density | 1.41 (NTP, 1992) |
| EC Number | 200-710-2 |
| Format | Powder |
| Grade | Cell Culture Grade |
| Hazard Statements | H317-H334 |
| Melting Point | 408 to 414° F (decomposes) (NTP, 1992) |
| Molecular Formula | C16H17N2O4SNa |
| Molecular Weight | 356.40 |
| Personal Protective Equipment | Dust mask, Eyeshields, Faceshields, Gloves |
| Potency | >1500 u/mg |
| RTECS Number | XH9800000 |
| Safety Symbol | GHS08 |
| Solubility | 50 to 100 mg/mL at 77° F (NTP, 1992) |
| Sterilization of Solutions | Solutions should be filter sterilized. Store in small aliquots at appropriate temperature until use. |
| Typical Working Concentration | For Gram Positive Bacteria=105 U/L |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Powered by Bioz