Dextran sulfate sodium salt, colitis grade (36,000 - 50,000)

Name: Dextran sulfate sodium salt, colitis grade (36,000 - 50,000)
SKU: 02160110-CF
Price: 106.45 USD

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SKU: 02160110-CF

Key features and details

Gold standard for colitis models – trusted worldwide, cited in 3,000+ publications
Superior quality – high sulfur content (17–20%)
Reproducible results – consistently outperforms competitor DSS in comparative studies
Protective packaging – pack sizes 25 g and larger are induction-sealed to prevent moisture ingress and safeguard product integrity
Flexible pack sizes – available from 1 g to 1 kg, with bulk and custom options

Synonyms

DSS, Dextran Sodium Sulfate

CAS Number:

9011-18-1

Molecular Weight:

36,000 - 50,000 Da

MDL Number:

MFCD00081551

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Product Description

Dextran sulfate sodium salt (DSS) is a synthetic sulfated polysaccharide derivative of dextran with wide use in biomedical and clinical research. Its most important application is the induction of colitis in rodent models. DSS binds to medium-chain fatty acids in the colon, disrupts the epithelial barrier, and triggers intestinal inflammation.

Because of its reproducibility and high efficacy, MP Biomedicals’ DSS is recognized as the gold standard reagent for colitis and colitis-associated cancer models. Over the past 19 years, DSS from MP Biomedicals has been cited in more than 3,000 peer-reviewed publications.

Application Notes

Ulcerative colitis models – commonly used in both acute and chronic induction protocols (2–5% DSS in drinking water for 5–7 days is standard)
Colitis-associated cancer models – often paired with azoxymethane (AOM), available separately from MP Biomedicals
Additional research areas – inflammatory bowel disease (IBD), gut microbiome interactions, and colon cancer

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Acute and chronic ulcerative colitis induction
Colitis-associated colon cancer induction

Specifications

SKU	02160110-CF
Alternate Names	DSS, Dextran Sodium Sulfate
Application Notes	Ulcerative colitis models – commonly used in both acute and chronic induction protocols (2–5% DSS in drinking water for 5–7 days is standard) Colitis-associated cancer models – often paired with azoxymethane (AOM), available separately from MP Biomedicals Additional research areas – inflammatory bowel disease (IBD), gut microbiome interactions, and colon cancer
Base Catalog Number	160110
CAS #	9011-18-1
Grade	Colitis Grade
Molecular Weight	36,000 - 50,000 Da
Personal Protective Equipment	Eyeshields, Gloves, respirator filter
pH	(1% aqueous solution) 5.0 - 7.5
RTECS Number	HH9290000
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.