Spermine

Name: Spermine
SKU: 02152070-CF
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SKU: 02152070-CF

Key features and details

Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.

Synonyms

Diaminopropyltetramethylenediamine; Gerontine; Musculamine; Neuridine; N,N-bis(aminopropyl)-1,4-butanediamine; 4,9-Diaza-1,12-dodecanediamine

CAS Number:

71-44-3

Molecular Formula:

C10H26N4

Molecular Weight:

202.3

Beilstein Registry Number:

1750791

EC Number:

200-754-2

MDL Number:

MFCD00008215

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Product Description

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

DNA precipitation | Chromosome isolation | Crystallization of DNA

Specifications

SKU	02152070-CF
Alternate Names	Diaminopropyltetramethylenediamine; Gerontine; Musculamine; Neuridine; N,N-bis(aminopropyl)-1,4-butanediamine; 4,9-Diaza-1,12-dodecanediamine
Base Catalog Number	152070
Beilstein Registry Number	1750791
Biochemical Physiological Actions	Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Boiling Point	141-142°C at 0.5 mm Hg;
CAS #	71-44-3
EC Number	200-754-2
Flash Point	110 °C / 230 °F (lit.)
Hazard Statements	H314
Melting Point	28-30°C (Lit.)
Molecular Formula	C10H26N4
Molecular Weight	202.3
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator ,Gloves, respirator cartridge, respirator filter
pH	11-14 (0.5% aq soln)
Purity	≥97%
RTECS Number	EJ7175000
Safety Symbol	GHS05
Solubility	Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.