Product Description
Guanosine-5′-Triphosphate Disodium Salt
Application Notes
Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF).
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Substrate for RNA polymerases
Specifications
| SKU | 0210071091 |
| Alternate Names | GTP disodium salt; 5′-GTP-Na2 |
| Application Notes | Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). |
| Base Catalog Number | 10071091 |
| Biochemical Physiological Actions | GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. |
| CAS # | 56001-37-7 |
| EC Number | 259-940-7 |
| Format | Powder |
| Molecular Formula | C10H14N5O14P3Na2 |
| Molecular Weight | 567.2 |
| Pack Size | 1 g |
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, Respirator filter |
| Purity | ≥98% |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | λ max (water): 252 ± 3 nm |
Documents
Certificate of Analysis (COA)
![MP COA [100710] lot ID: M9591](https://www.mpbio.com/static/version1742546773/frontend/Mpbio/default/en_US/images/document.png "MP COA [100710] lot ID: M9591")
Datasheet
Datasheet