Blasticidin S hydrochloride, phytopure™

Name: Blasticidin S hydrochloride, phytopure™
SKU: 02150477-CF
Price: 180.51 USD

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SKU: 02150477-CF

Key features and details

CAS Number: 3513-03-9

Synonyms

BLA-S; Cytovirin; Blasticidine S hydrochloride; 4-[[3-Amino-5-[(aminoiminomethyl)-1-oxopentyl]amino]-1-(4-amino-2-oxo- 1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-b-D-erythro-hex-2-enopyranuronic acid

CAS Number:

3513-03-9

Molecular Formula:

C₁₇H₂₆N₈O₅ - HCl

Molecular Weight:

458.90

MDL Number:

MFCD02091640

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Product Description

Broad spectrum nucleoside antibiotic. Inhibits protein synthesis in prokaryotic and eukaryotic organisms. Suitable for selection of cells carrying plasmids conferring blasticidin resistance.

Application Notes

Blasticidin S is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. Blasticidiin S has been used to select HEK293-T cells with TLR-2 constructs and HEK-D5 cells. It is also used to study protein synthesis at the level of peptide bond formation.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antimicrobial

Specifications

SKU	02150477-CF
Alternate Names	BLA-S; Cytovirin; Blasticidine S hydrochloride; 4-[[3-Amino-5-[(aminoiminomethyl)-1-oxopentyl]amino]-1-(4-amino-2-oxo- 1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-b-D-erythro-hex-2-enopyranuronic acid
Application Notes	Blasticidin S is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. Blasticidiin S has been used to select HEK293-T cells with TLR-2 constructs and HEK-D5 cells. It is also used to study protein synthesis at the level of peptide bond formation.
Base Catalog Number	150477
Biochemical Physiological Actions	Blasticidin S inhibits hydrolysis of peptidyl-tRNA induced by release factors. It enhances the binding of tRNA to the large subunit of ribosomes and to an extent inhibits peptide bond formation.
CAS #	3513-03-9
Hazard Statements	H300
Molecular Formula	C₁₇H₂₆N₈O₅ - HCl
Molecular Weight	458.90
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator , Gloves, respirator filter, respirator cartridges
RTECS Number	EC4900000
Safety Symbol	GHS06
Source	Streptomyces griseochromogenes
Typical Working Concentration	Typically used at 2 - 10 µg/mL for mammalian cell selection.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.